Klebl, Bert M. : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (44)
Les plus populaires
Liste
- Liste
- Tableau

1

Second-generation kinase inhibitors

Klebl, Bert M, Müller, Gerhard

Journal:

Expert Opinion on Therapeutic Targets

Année:

2005

Langue:

english

Fichier:

PDF, 873 KB

english, 2005

2

A Fluorometric Assay for Measurement of Mono-ADP-Ribosyltransferase Activity

Bert M. Klebl, Dirk Pette

Journal:

Analytical Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 161 KB

english, 1996

3

Generation of conditional lethal Candida albicans mutants by inducible deletion of essential genes

Sonja Michel, Sophia Ushinsky, Bert Klebl, Ekkehard Leberer, David Thomas, Malcolm Whiteway, Joachim Morschhäuser

Journal:

Molecular Microbiology

Année:

2002

Langue:

english

Fichier:

PDF, 973 KB

english, 2002

4

Synthesis of selective SRPK-1 inhibitors: Novel tricyclic quinoxaline derivatives

Zsolt Székelyhidi, János Pató, Frigyes Wáczek, Péter Bánhegyi, Bálint Hegymegi-Barakonyi, Dániel Ero˝s, György Mészáros, Ferenc Hollósy, Doris Hafenbradl, Sabine Obert, Bert Klebl, György Kéri, László

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2005

Langue:

english

Fichier:

PDF, 218 KB

english, 2005

5

Interplay between mycobacteria and host signalling pathways

Koul, Anil, Herget, Thomas, Klebl, Bert, Ullrich, Axel

Journal:

Nature Reviews Microbiology

Année:

2004

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2004

6

Evidence For In Vivo Inhibition of CMV Infection by the Quinazoline Class Protein Kinase Inhibitor Gefitinib

Mark Schleiss, Michael McVoy, Xiaohong Cui, Yeon Choi, Jodi Anderson, Thomas Stamminger, Bert Klebl, Jan Eickhoff, Manfred Marschall

Journal:

Antiviral Research

Année:

2007

Langue:

english

Fichier:

PDF, 75 KB

english, 2007

7

Protein kinase inhibitors of the quinazoline class exert anti-cytomegaloviral activity in vitro and in vivo

Mark Schleiss, Jan Eickhoff, Sabrina Auerochs, Martina Leis, Silke Abele, Sabine Rechter, Yeon Choi, Jodi Anderson, Gillian Scott, William Rawlinson, Detlef Michel, Stephan Ensminger, Bert Klebl, Thom

Journal:

Antiviral Research

Année:

2008

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2008

8

Stacking up the armory against viruses

Journal:

Drug Discovery Today

Année:

2004

Langue:

english

Fichier:

PDF, 41 KB

english, 2004

9

Specificity and Target Proteins of Arginine-Specific Mono-ADP-Ribosylation in T-Tubules of Rabbit Skeletal Muscle

Bert M. Klebl, Sven O. Göpel, Dirk Pette

Journal:

Archives of Biochemistry and Biophysics

Année:

1997

Langue:

english

Fichier:

PDF, 1.00 MB

english, 1997

10

A Comprehensive Analysis of Gene Expression Profiles in a Yeast N-Glycosylation Mutant

Bert Klebl, Detlef Kozian, Ekkehard Leberer, Maria A. Kukuruzinska

Journal:

Biochemical and Biophysical Research Communications

Année:

2001

Langue:

english

Fichier:

PDF, 62 KB

english, 2001

11

Localization of an arginine-specific mono-ADP-ribosyltransferase in skeletal muscle sarcolemma and transverse tubules

Bert M. Klebl, Shigeki Matsushita, Dirk Pette

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 559 KB

english, 1994

12

Protein oxidation, tyrosine nitration, and inactivation of sarcoplasmic reticulum Ca2+-ATPase in low-frequency stimulated rabbit muscle

Bert M Klebl, Ahmed T Ayoub, Dirk Pette

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 99 KB

english, 1998

13

O2-03-05: Gleevec increases levels of the APP intracellular domain (AICD) and the Abeta degrading enzyme neprilysin

Ellen Kilger, Yvonne S. Eisele, Matthias Baumann, Bert Klebl, Mathias Jucker

Journal:

Alzheimer's & Dementia

Année:

2006

Langue:

english

Fichier:

PDF, 58 KB

english, 2006

14

Chemical kinomics – a target gene family approach in chemical biology

Journal:

Drug Discovery Today: Technologies

Année:

2004

Langue:

english

Fichier:

PDF, 511 KB

english, 2004

15

Advances in Anti-Viral Therapeutics

Journal:

Expert Opinion on Investigational Drugs

Année:

2005

Langue:

english

Fichier:

PDF, 93 KB

english, 2005

16

A Flexible Multiwell Format for Immunofluorescence Screening Microscopy of Small-Molecule Inhibitors

Scholz, Anne-Kathrin, Klebl, Bert M., Morkel, Markus, Lehrach, Hans, Dahl, Andreas, Lange, Bodo M.H.

Journal:

Assay and Drug Development Technologies

Année:

2010

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2010

17

Drug Discovery in the Kinase Inhibitory Field Using the Nested Chemical Library™ Technology

Kéri, György, Székelyhidi, Zsolt, Bánhegyi, Péter, Varga, Zoltán, Hegymegi-Barakonyi, Bálint, Szántai-Kis, Csaba, Hafenbradl, Doris, Klebl, Bert, Muller, Gerhard, Ullrich, Axel, Erös, Dániel, Horváth,

Journal:

Assay and Drug Development Technologies

Année:

2005

Langue:

english

Fichier:

PDF, 185 KB

english, 2005

18

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Front Matter

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 155 KB

english, 2011

19

Evaluation of Kinase Inhibitor Selectivity by Chemical Proteomics

Daub, Henrik, Godl, Klaus, Brehmer, Dirk, Klebl, Bert, Müller, Gerhard

Journal:

Assay and Drug Development Technologies

Année:

2004

Langue:

english

Fichier:

PDF, 300 KB

english, 2004

20

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || In Vitro Characterization of Small-Molecule Kinase Inhibitors

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 942 KB

english, 2011

21

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Rational Drug Design of Kinase Inhibitors for Signal Transduction Therapy

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 374 KB

english, 2011

22

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Screening for Kinase Inhibitors: From Biochemical to Cellular Assays

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 224 KB

english, 2011

23

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Dissecting Phosphorylation Networks: The Use of Analogue-Sensitive Kinases and More Specific Kinase Inhibitors as Tools

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 258 KB

english, 2011

24

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || From Discovery to Clinic: Aurora Kinase Inhibitors as Novel Treatments for Cancer

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 304 KB

english, 2011

25

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Kinase Inhibitors in Signal Transduction Therapy

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 271 KB

english, 2011

26

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Medicinal Chemistry Approaches for the Inhibition of the p38 MAPK Pathway

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 385 KB

english, 2011

27

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Cellular Protein Kinases as Antiviral Targets

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 277 KB

english, 2011

28

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Prospects for TB Therapeutics Targeting Mycobacterium tuberculosis Phosphosignaling Networks

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 230 KB

english, 2011

29

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Design Principles of Deep Pocket-Targeting Protein Kinase Inhibitors

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2011

30

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG. O-BK) || Discovery and Design of Protein Kinase Inhibitors: Targeting the Cell Cycle in Oncology

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 531 KB

english, 2011

31

CDK9/cyclin T1: a host cell target for antiretroviral therapy

Klebl, Bert M, Choidas, Axel

Journal:

Future Virology

Année:

2006

Langue:

english

Fichier:

PDF, 257 KB

english, 2006

32

A Role for Myosin-I in Actin Assembly through Interactions with Vrp1p, Bee1p, and the Arp2/3 Complex

Marie Evangelista, Bert M. Klebl, Amy H. Y. Tong, Bradley A. Webb, Thomas Leeuw, Ekkehard Leberer, Malcolm Whiteway, David Y. Thomas and Charles Boone

Journal:

The Journal of Cell Biology

Année:

2000

Langue:

english

Fichier:

PDF, 2.96 MB

english, 2000

33

Professional translational research: a new hybrid paradigm in early drug discovery

Nussbaumer, Peter, Klebl, Bert

Journal:

Future Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 703 KB

english, 2015

34

Discovery of a Novel Hedgehog Signaling Pathway Inhibitor by Cell-based Compound Discovery and Target Prediction

Waldmann, Herbert, Kremer, Lea, Schultz-Fademrecht, Carsten, Baumann, Matthias, Habenberger, Peter, Choidas, Axel, Klebl, Bert, Kordes, Susanne, Schöler, Hans J., Sterneckert, Jared, Ziegler, Slava, S

Journal:

Angewandte Chemie International Edition

Année:

2017

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2017

35

Discovery of a Novel Hedgehog Signaling Pathway Inhibitor by Cell-based Compound Discovery and Target Prediction

Waldmann, Herbert, Kremer, Lea, Schultz-Fademrecht, Carsten, Baumann, Matthias, Habenberger, Peter, Choidas, Axel, Klebl, Bert, Kordes, Susanne, Schöler, Hans J., Sterneckert, Jared, Ziegler, Slava, S

Journal:

Angewandte Chemie

Année:

2017

Fichier:

PDF, 1.09 MB

2017

36

Identification of an (-)-Englerin A analogue which antagonizes (-)-Englerin A at TRPC1/4/5 channels

Rubaiy, Hussein N, Seitz, Tobias, Hahn, Sven, Choidas, Axel, Habenberger, Peter, Klebl, Bert, Dinkel, Klaus, Nussbaumer, Peter, Waldmann, Herbert, Christmann, Mathias, Beech, David J

Journal:

British Journal of Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 726 KB

english, 2017

37

Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes

Bongard, Jens, Lorenz, Marian, Vetter, Ingrid R., Stege, Patricia, Porfetye, Arthur T., Schmitz, Anna Laura, Kaschani, Farnusch, Wolf, Alex, Koch, Uwe, Nussbaumer, Peter, Klebl, Bert, Kaiser, Markus,

Journal:

ACS Chemical Biology

Année:

2018

Langue:

english

Fichier:

PDF, 3.16 MB

english, 2018

38

Gasdermin D plays a vital role in the generation of neutrophil extracellular traps

Sollberger, Gabriel, Choidas, Axel, Burn, Garth Lawrence, Habenberger, Peter, Di Lucrezia, Raffaella, Kordes, Susanne, Menninger, Sascha, Eickhoff, Jan, Nussbaumer, Peter, Klebl, Bert, Krüger, Renate,

Journal:

Science Immunology

Année:

2018

Langue:

english

Fichier:

PDF, 7.22 MB

english, 2018

39

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG.) || Index

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 60 KB

english, 2011

40

A Role for Myosin-I in Actin Assembly through Interactions with Vrp1p, Bee1p, and the Arp2/3 Complex

Evangelista, Marie, Klebl, Bert M., Tong, Amy H.Y., Webb, Bradley A., Leeuw, Thomas, Leberer, Ekkehard, Whiteway, Malcolm, Thomas, David Y., Boone, Charles

Journal:

The Journal of Cell Biology

Année:

2000

Langue:

english

Fichier:

PDF, 347 KB

english, 2000

41

Chemical validation of DegS as a target for the development of antibiotics with a novel mode of action

Bongard, Jens, Schmitz, Anna Laura, Wolf, Alex, Zischinsky, Gunther, Pieren, Michel, Schellhorn, Birgit, Bravo-Rodriguez, Kenny, Schillinger, Jasmin, Koch, Uwe, Nussbaumer, Peter, Klebl, Bert, Steinma

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 1.84 MB

english, 2019

42

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A

Cheung, Sin Ying, Henrot, Matthias, Al-Saad, Mohammad, Baumann, Matthias, Muller, Heiko, Unger, Anke, Rubaiy, Hussein N., Mathar, Ilka, Dinkel, Klaus, Nussbaumer, Peter, Klebl, Bert, Freichel, Marc, R

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 5.19 MB

english, 2018

43

[Methods and Principles in Medicinal Chemistry] Protein Kinases as Drug Targets (KLEBL:KINASES DRUG TARG.) ||

Klebl, Bert, Müller, Gerhard, Hamacher, Michael

Année:

2011

Langue:

english

Fichier:

PDF, 4.26 MB

english, 2011

44

Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia

Johansson, Patricia, Dierichs, Laura, Klein-Hitpass, Ludger, Bergmann, Anke K., MÃ¶llmann, Michael, Menninger, Sascha, Habenberger, Peter, Klebl, Bert, Siveke, Jens T., DÃ¼hrsen, Ulrich, Choidas, Axel

Journal:

Therapeutic Advances in Hematology

Année:

2020

Fichier:

PDF, 3.02 MB

2020